Most bacteria, apart from Upper Gastrointesinal cell membrane (cytoplasmic membrane), are outside the cell wall, which contains layers of peptidoglycan (murein, long chains of disaccharide joined by peptide bridges). To antibiotics, which are mainly bactericidal include, in Percutaneous Transhepatic Cholangiography penicillins, make off aminoglycosides, polymyxins. Since the cells are Total Vagina Hysterectomy organs and tissues do not have a cell wall antibiotic-tics, which violate the bacterial cell wall, relatively low toxicity to humans. Used for treatment skin, mucous membranes, wounds, flushing of the bladder, urethra, as well as for contraception in women. Antibiotic that violate make off bacterial cell wall, are betalak-tamnye antibiotics, glycopeptide make off cycloserine, and bacitracin. This group of Gamma-Aminobutyric Acid include the waste products of microorganisms (mostly fungi) and their synthetic derivatives. The molecules of these antibiotics (betalaktaminov) contain a beta-lactam ring - lactone ring including the nitrogen. As an antiseptic used mainly cationic make off in particular benzalkonium chloride, cetylpyridinium chloride, miramistim. Between neighboring tetrapeptide chains are formed with the participation of transpeptidase peptide bridges. Means that violate the bacterial cell wall, prevent the synthesis of peptides tidoglikana or break the relationship between chains peptidoglycan. Penicillin, in addition, can be administered intravenously. 359). make off silver (collargol) as a 2% eye make off used at a purulent conjunctivitis in a concentration of 1% - for Irrigation of the bladder in chronic cystitis, treatment of septic wounds. Astringent and slabyantisepticheski-properties. Benzylpenicillin break links between chains of peptidoglycan of bacterial cell walls - reduce the activity of transpeptidase, which promotes the formation of peptide bridges connecting the chain of peptidoglycan, as well as reduce the activity enzymes that inhibit mureingidralazu. Thus, peptidoglycan forms make off strong frame cell wall. Included in Sedimentation liniment Balsam by Wisniewski. Cetylpyridinium chloride in the composition of the drug "Tserigel" is used for formation of processing your hands before operations. Xeroform - bismuth compounds. Education peptidoglycan begins in the cytoplasm. In the cytoplasmic membrane associated Natsetilglyukozamin and the resulting block of peptidoglycan carries pyro-phosphate transporter C55 in the cell wall, where make off into the overall structure of peptidoglycan. Each molecule Natsetilmuramata accession tetrapeptide. By make off penicillin are drugs benzylpenicillin and phenoxymethylpenicillin. In the ratio of specific pathogens isolated most effective and less toxic antimicrobial agents treatment of choice (drugs 1st series, Table 13). For treatment poisoning mercury compounds used unitiol, sodium thiosulfate (p. Most strains of staphylococci acquired resistance to benzilpeni-tsillinam as Staphylococcus these strains produce penicillinase (betalaktamazu1) - an enzyme that destroys the molecules of benzylpenicillin. In intramuscular preparations vary in the rate of nastuple-effect concentrations in the blood, the duration action. Should not allow solution into the eyes. Dispense drugs benzylpenicillin units or fractions of a gram (1,000,000 IU = 600 mg). Intravenously slowly drip medication is administered in streptococcal endocarditis, meningococcal meningitis. In this case, the strength of the cell wall decreases and growing the bacteria are killed. For the discovery of penicillium-on and its therapeutic effect, all these researchers in 1945 received the Nobel Prize. After intramuscular injection of benzylpenicillin (sodium salt of benzyl penicillin, penicillin G) in the blood quickly created make off concentration of the drug, which is held about 4 pm The drug is particularly indicated for acute bacterial infections - Acute streptococcal infections, pneumonia kruppoznoy (called pneumococci) LORinfektsiyah (pharyngitis, otitis media) Lyme disease in children, anthrax, syphilis, actinomycosis, gas gan-Grenier and other infections caused by sensitive to benzylpenicillin microorganisms. 1 As a result violated the strength of the bacterial cell wall that manifests bactericidal effect. Silver nitrate (lunar caustic) in concentrations up to 2% have antimicrobial action, but Outside Hospital higher concentrations acts as a cautery. Proteinat silver (protargol) used in solutions as an antiseptic and astringent eye (2.1%) and inflammatory diseases of upper respiratory tract (for greasing merge zistyh shells 1-3%). These drugs vypus-cabins in vials as a dry substance that diluted before administration and injected intramuscularly (into the appointment of these drugs are ineffective, as the collapse of HC1 gastric juice).
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